Press release
Pigmented Villonodular Synovitis Treatment Market Trends, Business Strategies and Opportunities, Forecast 2017 - 2025
The objectives of this study are as follows:
To define, describe, and forecast the "Pigmented Villonodular Synovitis Treatment" market by type, application, component, delivery model, end user, and region
To provide detailed information regarding major factors influencing market growth (drivers, restraints, opportunities, and industry-specific challenges)
To analyze micromarkets with respect to individual growth trends, prospects, and contributions to the overall market
To analyze opportunities in the market for stakeholders and provide details of the competitive landscape for market leaders
To forecast the market size of market segments with respect to the four key regions: North America, Europe, Asia, and the Rest of the World (RoW)
To strategically profile the key players and comprehensively analyze their product portfolios, market positions, and core competencies
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Pigmented villonodular synovitis (PVNS) is a rare benign proliferative (overgrowth) form that affects the synovial membrane (also termed as stratum synoviale or synovium). Synovial membrane is a thin sheet of connective tissue that lines the inner surface of capsules of tendon sheath and synovial joints. The cell bulk or lump that results from overgrowth is not carcinogenic and does not spread to other parts of the body by metastasis. PVNS is a progressive disease that gradually becomes worse and can lead to arthritis and damage the bones. PVNS is mostly monoarticular (affects only one joint of the body or affects around 70% part of knee joint), but it can also be oligoarticular (affecting a few joints). The histology of PVNS are similar to some violent neoplasms (epithelioid sarcoma, synovial sarcoma, and rhabdomyosarcoma), therefore, has an important role in managing the pathologist. Radiographs show general characteristics such as bone erosions and joint effusion. Ultrasound and CT scan can also show the hypertrophic synovium as a slightly echogenic/hyper dense soft tissue bulk. MRI is the best method that shows the mass like synovial propagation with lobulated margins, with small signal intensity and “blooming” structure on gradient echo. These gradient echoes are due to deposition of hemosiderin (an iron-storage complex).
Mostly PVNS occurs in persons with starting of mid age. There is no gender predilection for intra articular disease, whereas extra articular disease has a minor female predominance. Symptoms in PVNS include joint dysfunction, pain, and sometimes joint inflammation. Mostly, symptoms have been exist for several months before the analysis is done. It is rare among children; however, it occasionally occurs and is more often polyarticular. It can also been defined in relation with: vascular lesions, Noonan syndrome, multiple lentigines syndrome, mandibular lesions, extremity lymphedema, and cherubism. Treatment includes surgery to eliminate the tumor (lumps) and the injured parts of the joint lining. When local PVNS has also injured a tendon, doctor will repair it by removing the tumor.
Rise in concerns and awareness related to health and increased prevalence of the disease are the major factors fueling the growth of the pigmented villonodular synovitis treatment market. Moreover, availability of advanced medications and surgical procedures are the other factors driving the market. However, unawareness about disease and less availability of advanced resources and medical facilities in underdeveloped countries restrain the market.
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The global pigmented villonodular synovitis treatment market can be segmented based on type of treatment, end-user, and region. In terms of type of treatment, the market can be classified into drug therapy, radiation therapy, and surgical operation. The drug therapy segment can be sub-segmented into cabiralizumab, emactuzumab, mcs-110, nilotinib, and others. The surgical operation segment can be divided into arthroscopy, open surgery, combined arthroscopic and open surgery, and total joint replacement. Based on end-user, the global villonodular synovitis treatment market can be categorized into hospitals, surgical clinics, and others.
In terms of region, the global pigmented villonodular synovitis treatment market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is expected to dominate the global pigmented villonodular synovitis treatment market due to availability of advanced surgical procedures, medications, and other therapies such as radiation therapy. Awareness among the people about the diseases is another factor boosting the market in this region. The pigmented villonodular synovitis treatment market in Asia Pacific is anticipated to expand at a high growth rate due to increase in prevalence of the disease.
Key players operating in the global pigmented villonodular synovitis treatment market are Plexxikon, Inc., Novartis AG, F. Hoffmann-La Roche Ltd., and Bristol-Myers Squibb Company, among others.
The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.
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The study is a source of reliable data on:
Market segments and sub-segments
Market trends and dynamics
Supply and demand
Market size
Current trends/opportunities/challenges
Competitive landscape
Technological breakthroughs
Value chain and stakeholder analysis
The regional analysis covers:
North America (U.S. and Canada)
Latin America (Mexico, Brazil, Peru, Chile, and others)
Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, and Luxembourg)
Eastern Europe (Poland and Russia)
Asia Pacific (China, India, Japan, ASEAN, Australia, and New Zealand)
Middle East and Africa (GCC, Southern Africa, and North Africa)
The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.
A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.
Highlights of the report:
A complete backdrop analysis, which includes an assessment of the parent market
Important changes in market dynamics
Market segmentation up to the second or third level
Historical, current, and projected size of the market from the standpoint of both value and volume
Reporting and evaluation of recent industry developments
Market shares and strategies of key players
Emerging niche segments and regional markets
An objective assessment of the trajectory of the market
Recommendations to companies for strengthening their foothold in the market
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