Tissue Engineering Market Growth, Size, Comparative Analysis and Key Players Acelity L.P, Allergan, Athersys, B. Braun, BioMimetic Therapeutics, Bio Tissue Technologies

Tissue engineering is an interdisciplinary field addressed to develop functional three-dimensional tissues combining cells, scaffolds, and bioactive molecules. This field involves scientific areas such as cell biology, chemistry, material science, molecular biology, medicine, and engineering. It can be used to develop functional constructs that can be used to reestablish, maintain or improve the condition of injured body parts or tissues.

Tissue engineering also assist in regeneration of damaged tissues by combining cells from the body with highly porous scaffold biomaterials. Scaffold biomaterials act as templates for tissue regeneration and guide the growth of new tissue. Tissue regeneration is highly beneficial for clinical management of organ therapeutics such as organ transplantation. The source of cells utilized in tissue engineering can be autologous (from the patient), allogenic (from a human donor but not immunologically identical), or xenogenic (from a different species donor).

The global tissue engineering market size was valued at US$ 5.5 billion in 2017, and is expected to witness a CAGR of 11.5% over the forecast period (2018 – 2026).

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Shortage of donor for various transplantation procedures presents a severe challenge to clinicians worldwide. According to the U.S. government information on organ donation and transplantation, as of 2017 nearly 114,687 people in the U.S. were on waiting lists for transplants of kidneys, hearts, livers, and other organs. Tissue engineering can fulfil the inadequacy of organ transplantation and increasing 3D printing prominence in medical applications for regeneration is anticipated to propel the demand for tissue engineering during the forecast period. Tissue engineering also holds a promising future for the restoration of 3D contour as well as the loss of function for the affected body parts.

Tissue Engineering Market Restraints

Currently available tissue engineering methods face several problems including ineffective cell growth, insufficient, and unstable production of growth factors to stimulate cell communication and proper response and lack of suitable biomaterials and techniques for capturing appropriate physiological architectures. Moreover, inability to control cellular functions and their various properties (biological, mechanical, electrochemical and others) and issues of biomolecular detection and biosensors are other limitations associated with tissue engineering.

Furthermore, despite the growing interest in tissue engineering research, progress has been hampered by ethical and legislative debates. For instance, the ethical, political, and religious opposition for embryonic stem cell research, which primarily uses discarded non-transferred human embryos for their derivation, have biased research toward adult stem cells and severely restricted federal funding in the U.S.

Tissue Engineering Market - Regional Insights

On the basis of region, the global tissue engineering market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to foresee significant growth by 2026, owing to increasing geriatric population and research studies in the field of tissue engineering. For instance, in August 2018, bioengineers at the Pennsylvania State University developed a composite ink to 3-D print porous, bone-like constructs. The materials showed biologically favorable interactions in the laboratory, followed by positive outcomes of bone regeneration in an animal model in vivo.

Europe tissue engineering market is expected to grow at lucrative rate, owing to presence of various public and private organizations focusing on research in tissue engineering field. For instance, in UK, most tissue engineering research takes place in universities and much of the funding comes from organizations supporting the development of bioengineered organs for drug testing, including the Refinement and Reduction of Animals in Research (NC3Rs) National Centre for the Replacement and the EU’s Innovative Medicines Initiative.

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