HER2+ Breast Cancer Market Report- In-Depth Analysis of Industry Share, Size, Growth Outlook up to 2025

HER2+ Breast Cancer Market report covers the forecast and analysis for the global market on a worldwide and regional level. In addition, HER2+ Breast Cancer Market report includes the positive and the negative factors that influence the growth of the market. HER2+ Breast Cancer Market report covers vital regions like North America, South America, Europe, and the rest of the world.

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Breast cancer is the second most common cancer in the world and the most common cancer in women worldwide. Human epidermal growth factor receptor 2-positive (HER2+) breast cancer constitutes approximately 20% of breast cancer cases and was historically associated with poor prognosis in the absence of effective treatments. The realization that introducing HER2-targeted therapies earlier into the disease management strategy could improve disease-free survival (DFS) has created a large market for HER2-directed therapies. Today, HER2+ breast cancer patients are living longer with their disease, thanks to established disease management strategies using regimens with Herceptin, Perjeta, and the antibody-drug conjugate Kadcyla. During the forecast period 2020-2030, each of these agents are expected to face patent expiries and biosimilar erosion, which will represent the biggest barrier of market growth to date. To combat biosimilar erosion, Roche/Genentech is developing subcutaneous fixed-dose formulations of Herceptin/Perjeta to provide convenience for patients and physicians. This will act to consolidate revenues for Roche/Genentech and maintain their presence as market leader throughout the forecast period. Daiichi Sankyo and AstraZeneca’s agent, Enhertu is expected to make a large impact of clinical practice by replacing Kadcyla in the second-line metastatic setting and threatening it’s patient share in the adjuvant setting. RNR anticipates 5 pipeline agents to be launched across the 8MM over the forecast period 2020-2030. The HER2+ market is forecast to grow to $12.1B by 2030, at a Compound Annual Growth Rate (CAGR) of 1.5%.

HER2+ Breast Cancer Market report covers opportunities for various marketed agents and pipeline agents in development across the 8MM, clinical and commercial assessments for agents in late-stage clinical development, R&D strategies, and innovative approaches in development for HER2+ breast cancer. This edition provides an update to the previous sales forecast for marketed and pipeline agents and highlights expected market dynamics by country and class of therapy across the forecast period, 2020-2030.

KEY QUESTIONS ANSWERED-
- 5 late-stage pipeline agents are going to enter the HER2+ market from 2020 onwards. Will the impact will these agents have on the market? Which of these drugs will have the highest peak sales, and why?
- What are the current unmet needs in HER2+ breast cancer, which pipeline agents are positioned to counter these unmet needs? What are the opportunities for R&D?
- What is the market outlook in the 8MM from 2020-2030? Considering major patent expiries, launch of new premium priced agents and expected label expansions.
- What are the main corporate trends? Who are the current and future players?

Key Highlights -
- The main drivers of growth include the anticipated label expansion of currently marketed therapies, subcutaneous reformulations of blockbuster drugs and the approval and launch of 5 pipeline therapies and greater market access across the 8MM for premium priced agents
- The main barriers to growth in the 8MM are the patent expiries of the leading brands across the 8MM, in particular Perjeta, Herceptin and Kadcyla, which constituted the majority of sales in 2020
- The most important unmet needs in the HER2+ market include: Efficacious treatments for patients with brain metastases, tackling intratumor heterogeneity and improving patient outcomes

Scope of this Report-
- Overview of HER2+ breast cancer including epidemiology, etiology, pathophysiology, symptoms, diagnosis, and treatment guidelines.
- Topline HER2+ market revenue, annual cost of therapy, and major pipeline product sales in the forecast period.
- Key topics covered include current treatment and pipeline therapies, unmet needs and opportunities, and the drivers and barriers affecting HER2+ therapeutics sales in the 8MM.
- Pipeline analysis: Comprehensive data split across different phases, emerging novel trends under development, and detailed analysis of late-stage pipeline drugs (Phase III).
- Analysis of the current and future market competition in the global HER2+ market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to Buy this Report-
The report will enable you to -
- Develop and design your in-licensing and out-licensing strategies, using a detailed overview of current pipeline products and technologies to identify companies with the most robust pipelines.
- Develop business strategies by understanding the trends shaping and driving the global HER2+ therapeutics market.
- Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global HER2+ market in the future.
- Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
- Track drug sales in the global HER2+ therapeutics market from 2020-2030.
- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

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List of Tables in this Report-
Table 1: HER2+ Breast Cancer: Key Metrics in the 8MM
Table 2: Inherited Gene Mutations Associated with Lifetime Breast Cancer Risk
Table 3: Established and Probable Risk Factors Associated with Breast Cancer Development
Table 4: Molecular Subtypes of Breast Cancer
Table 5: AJCC Stage Definitions for Breast Cancer
Table 6: Risk Factors and Comorbidities for All Invasive HER2-Positive Breast Cancer
Table 7: Treatment Guidelines for HER2+ Breast Cancer
Table 8: Overview of Key Pivotal Phase II/III Trials in HER2+ Breast Cancer
Table 9: Top 10 Deals by Value, 2018-2020
Table 10: HER2+ Breast Cancer Market - Global Drivers and Barriers, 2020-2030
Table 11: Key Events Impacting Sales for HER2+ Breast Cancer in the US, 2020-2030
Table 12: HER2+ Breast Cancer Market - Drivers and Barriers in the US, 2020-2030
Table 13: Key Events Impacting Sales for HER2+ Breast Cancer in the 5EU, 2020-2030
Table 14: HER2+ Breast Cancer Market - Drivers and Barriers in the 5EU, 2020-2030
Table 15: Key Events Impacting Sales for HER2+ Breast Cancer in Japan, 2020-2030
Table 16: HER2+ Breast Cancer Market - Drivers and Barriers in Japan, 2020-2030
Table 17: Key Events Impacting Sales for HER2+ Breast Cancer in China, 2020-2030
Table 18: HER2+ Breast Cancer Market - Drivers and Barriers in China, 2020-2030
Table 19: High-Prescribing Physicians (non-KOLs) Surveyed, By Country

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