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Hereditary Angioedema - Pipeline Assessment, 2023 Updates | In-depth Insights into the Clinical Trials, Emerging Drugs, Latest FDA, EMA, and PMDA Approvals, and Treatment Outlook | Astria Therapeutics Inc, Attune Pharmaceuticals, BioMarin Pharmaceutical
Hereditary Angioedema
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Hereditary Angioedema is an infrequent inherited disease that causes substantial swelling in various body tissues, such as the abdomen or face caused by a low level or improper function of a protein called the C1 inhibitor. There are three types of hereditary angioedema namely type I, II, and III.
Hereditary Angioedema is mainly caused by a low level or improper function of a protein called C1 inhibitor.
Symptoms are severe abdominal pain and cramping, dehydration, diarrhea and shock, hoarse voice, difficulty swallowing, and difficulty breathing.
Hereditary Angioedema is diagnosed by blood tests that detect decreased levels of complement proteins and erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels.
Hereditary Angioedema is treated by medications, such as corticosteroids, antihistamines and epinephrine.
Read more about Hereditary Angioedema Insight here: https://www.globalinsightservices.com/reports/hereditary-angioedema-drug-pipeline-landscape/
Major pharmaceutical companies are involved in the development of potential drug candidates to improve the treatment of Hereditary Angioedema treatment such as CSL312, Sebetralstat, BMN 331, PHVS719, and others. Key players involved in the development of therapies to treat Hereditary Angioedema are CSL Behring, Kalvista Pharmaceuticals and others. Four drugs are under late-stage Phase III clinical trials and three drugs are in Phase II clinical trials and some other drugs are under Phase I, preclinical and discovery stages of development.
In Nov 2022, Ionis Pharmaceuticals Inc presented positive Phase II study of open label extension results of donidalosen. In Oct 2022, KalVista Pharmaceuticals announced positive Phase I data of sebetralstat. In August 2022, Global Biotechnology announed positive top-line Phase III results for garadacimab.
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Report Covers the Emerging Pipeline Products Under Different Phases of Clinical Development Like:
- Late-stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I)
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
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Hereditary Angioedema is an infrequent inherited disease that causes substantial swelling in various body tissues, such as the abdomen or face caused by a low level or improper function of a protein called the C1 inhibitor. There are three types of hereditary angioedema namely type I, II, and III.
Hereditary Angioedema is mainly caused by a low level or improper function of a protein called the C1 inhibitor.
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