Endogenous Cushing's Syndrome Market Trends Analysis, Growth Opportunities and Challenges, Clinical Activities, Leading Companies, Emerging Therapies, and Epidemiology Forecast | Corcept Therapeutics, Cortendo AB

DelveInsight's "Endogenous Cushing's Syndrome Market Insights, Epidemiology, and Market Forecast 2032" report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the Endogenous Cushing's Syndrome Market Size and Share in the seven major markets (7MM) (i.e., the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom and Japan).

The market report covers emerging drugs, treatment practices, market share of individual Endogenous Cushing's Syndrome therapies, and current & forecasted market size from 2019 to 2032. It also evaluates the current Endogenous Cushing's Syndrome treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of opportunities and assess the underlying potential of the market.

Endogenous Cushing's Syndrome: An Overview
Cushing syndrome is a rare endocrine disorder characterized by various symptoms and physical abnormalities that occur due to excessive amounts of the hormone cortisol, a vital glucocorticoid. Endogenous Cushing syndrome is defined as the syndrome in which the adrenal glands produce too much cortisol. It is one of two types of Cushing syndrome. The other type is exogenous in which glucocorticoids are introduced from outside the body. Endogenous Cushing's syndrome is a rare, serious, and potentially lethal endocrine disease caused by chronic elevated cortisol exposure - often the result of a benign pituitary gland tumor.

The diagnosis of Cushing syndrome due to endogenous overproduction of cortisol requires the demonstration of inappropriately high serum cortisol or urine cortisol levels. Currently, four methods are accepted for the diagnosis of Cushing syndrome: urinary free cortisol level, low-dose dexamethasone suppression test, evening serum and salivary cortisol level, and dexamethasone-corticotropin-releasing hormone test.

Treatment of Cushing syndrome is directed by the primary cause of the syndrome. In general, therapy is aimed to reduce cortisol secretion to normal to reduce the risk of comorbidities associated with hypercortisolism. The treatment of choice for endogenous Cushing syndrome is surgical resection of the causative tumor.

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Endogenous Cushing's Syndrome Market Key Facts
• The Endogenous Cushing's Syndrome therapeutics market is anticipated to grow in the coming years owing to the increase in the incidence of Endogenous Cushing's Syndrome, along with the expected launch of emerging therapies. The pipeline for Endogenous Cushing's Syndrome brings a positive ray of hope for a better treatment pattern in the market in the upcoming years.
• Various Key players such as Corcept Therapeutics, Cortendo AB (a subsidiary of Strongbridge Biopharma), and others are in the process of developing potential therapies for the treatment of Endogenous Cushing's Syndrome.
• According to the National Organization of Rare Disorders (NORD) (n.d.), Cushing syndrome, caused by an adrenal or pituitary tumor, affects females five times more frequently than males. Symptoms commonly begin between 25 to 40 years of age. Men are affected 3 times more than women by ectopic ACTH production that is caused by lung cancer, which occurs later in life.
• According to the National Institute of Diabetes and Digestive and Kidney Diseases, Cushing's syndrome most often affects adults, usually aged 30 to 50, but can also occur in children. Cushing's syndrome affects about three times as many women as men.

Endogenous Cushing's Syndrome Market
The market outlook section of the report helps to build a detailed comprehension of the historical, current, and forecasted market size by analyzing the impact of current and emerging Endogenous Cushing's Syndrome therapies in the market. It also provides a detailed assessment of the Endogenous Cushing's Syndrome market drivers & barriers, unmet needs, and emerging technologies.

The report gives complete detail of the market trend for each marketed Endogenous Cushing's Syndrome drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MOA), competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.

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Endogenous Cushing's Syndrome Epidemiology
The epidemiology section covers detailed insights into the historical, and current Endogenous Cushing's Syndrome patient pool and forecasted epidemiology trends for every seven major countries (7MM) from 2019 to 2032.

The Report Covers the Endogenous Cushing's Syndrome Epidemiology, Segmented by -
• Total Incident Cases of Endogenous Cushing's Syndrome in the 7MM (2019-2032)
• Gender-Specific Incident cases of Endogenous Cushing's Syndrome in the 7MM (2019-2032)
• Treatable cases of Endogenous Cushing's Syndrome in the 7MM (2019-2032)

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Endogenous Cushing's Syndrome Drugs Uptake and Pipeline Development Activities
The drugs' uptake section focuses on the rate of uptake of the potential drugs recently launched in the Endogenous Cushing's Syndrome market or expected to be launched during the study period. The analysis covers the market share by Endogenous Cushing's Syndrome drugs, patient uptake by therapies, and sales of each drug.

The report's drugs uptake section helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs. It allows the comparison of the drugs based on market share and size, which again will be helpful in investigating factors important in understanding the market dynamics and in making financial and regulatory decisions.

The report also covers the Endogenous Cushing's Syndrome Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyses recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

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Endogenous Cushing's Syndrome Companies in the Therapeutics Market Include:
• Corcept Therapeutics
• Cortendo AB (a subsidiary of Strongbridge Biopharma)
And Many Others

Endogenous Cushing's Syndrome Therapies Covered in the Report Include:
• Recorlev (Strongbridge Biopharma plc)
• Relacorilant (Corcept Therapeutics)
And Many Others

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Table of Content (TOC)
1. Key Insights
2. Executive Summary
3. Endogenous Cushing's Syndrome Competitive Intelligence Analysis
4. Endogenous Cushing's Syndrome Market Overview at a Glance
5. Endogenous Cushing's Syndrome Background and Overview
6. Endogenous Cushing's Syndrome Patient Journey
7. Endogenous Cushing's Syndrome Epidemiology and Patient Population
8. Endogenous Cushing's Syndrome Treatment Algorithm, Current Treatment, and Medical Practices
9. Endogenous Cushing's Syndrome Unmet Needs
10. Key Endpoints of Endogenous Cushing's Syndrome Treatment
11. Endogenous Cushing's Syndrome Marketed Products
12. Endogenous Cushing's Syndrome Emerging Therapies
13. Endogenous Cushing's Syndrome Seven Major Market Analysis
14. Attribute Analysis
15. Endogenous Cushing's Syndrome Market Outlook (7 major markets)
16. Endogenous Cushing's Syndrome Access and Reimbursement Overview
17. KOL Views on the Endogenous Cushing's Syndrome Market.
18. Endogenous Cushing's Syndrome Market Drivers
19. Endogenous Cushing's Syndrome Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
*The table of contents is not exhaustive; the final content may vary.

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