Peripheral Liquid Embolic Agents Market to enhance user interface is expected to boost growth of the market

The Peripheral Liquid Embolic Agents Market is expected to grow from US$ 40.42 million in 2023 to US$ 81.41 million by 2031; it is anticipated to record a CAGR of 9.1% from 2023 to 2031.

Peripheral liquid embolic agents are substances used in interventional radiology procedures to block leaking blood vessel and malformations. These agents solidify after injecting which forms plug and block the blood flow to the targeted area.

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Analysis of the Top Market Players:

1. Medtronic
2. B Braun SE
3. Guerbet SA
4. Sirtex Medical Ltd
5. Balt
6. MicroVention Inc
7. Johnson & Johnson
8. GEM srl

In this report, the market has been segmented on the basis of:

Type

• Polymerizing Liquid Embolic Agent
• Precipitating Liquid Embolic Agent

Application

• Endoleak Type II
• Malformations
• Bleedings and Trauma
• Varicose Vein
• Tumors
• Visceral Aneurysm

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Developments in Temperature-Induced Phase Change Systems and pH-Triggered Embolic Agents Acts as a Trend for Market Growth

Liquid embolism is a topic of great interest in bioengineering, particularly in peripheral procedures. Liquid embolic agents can penetrate peripheral, nidus, or distal areas where coils or catheters cannot reach. Although currently used liquid embolic agents can meet most clinical needs, they have some shortcomings. Therefore, various novel liquid embolic agents have been developed to improve imaging characteristics, reduce complications, optimize flow performance, and achieve drug loading capability. The systematic investigation of additional important material characteristics such as associated side effects (e.g., toxicity and adhesion), biofunctional (biocompatibility, biodegradability, biomechanics, and bioactivity), and radiopacity is essential for the development of clinically tailored embolic agents in the field of minimally invasive imaging procedures.

Temperature-sensitive polymer solutions can change from a sol-injectable state to a gel state at room temperature in the body. Poly(N-isopropyl acrylamide) (PNIPAAm) exhibits a reversible phase transition in response to a lower critical solution temperature (LCST) of 32 °C. According to a study published in the Journal of Controlled Release by Qian et al. in 2015, poly(N-isopropylacrylamide-co-butylmethyl acrylate) gels with iohexol dispersions for TACE of liver cancer demonstrated effective embolization of renal arteries in rabbits and sustained release of doxorubicin.

Similarly, as per a study published in the National Library of Medicine by Wang et al. in 2011, chitosan/β-glycerophosphate (C/GP) successfully closed renal arteries in rabbits, indicating to be a potential embolization agent. Likewise, Zhao et al. also investigated temperature-sensitive PNIPAAm-iohexol nano gels for embolization, according to a research study published Wiley Online Library in 2011. The hydrophobic interactions above the phase transition temperature (36.5 °C) lead to a hierarchical 3D gel network for in situ vessel casting. Compared to Lipiodol, a peripheral embolic agent, the nanogel provided better peripheral embolization in VX2 liver tumors in rabbits.

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