Press release
Graves Ophthalmopathy Pipeline Therapeutics Assessment Report 2024 (Updated)
Graves Ophthalmopathy Pipeline
Explore our latest breakthroughs in Graves Ophthalmopathy Research. Learn more about our innovative pipeline today! @ Graves Ophthalmopathy Pipeline Outlook- https://www.delveinsight.com/sample-request/graves-ophthalmopathy-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr
Key Takeaways from the Graves Ophthalmopathy Pipeline Report
• In November 2024:- Viridian Therapeutics- This is a randomized (meaning participants will be assigned to study arms by chance), double-masked (meaning study doctor and participant will not know which study arm participant is assigned to), placebo-controlled study that will include participants with chronic TED. The key objectives of this study are to determine if VRDN-003 is efficacious, safe and tolerable when administered as subcutaneous/SC injections every 4 weeks or every 8 weeks compared to placebo in participants with chronic TED.
• In November 2024:- Amgen- The main objective of the study is to evaluate the effect of teprotumumab subcutaneous administration versus placebo on the proptosis responder rate (ie, the percentage of participants with a ≥ 2-mm reduction from Baseline in the study eye without deterioration [≥ 2-mm increase] of proptosis in the fellow eye) at Week 24. The study consists of a randomized double-masked, placebo-controlled, parallel-group, multicenter trial with an optional open-label treatment period for proptosis non-responders who complete the Double-masked Treatment Period.
• In November 2024:- ACELYRIN Inc.- A Phase 1/2, Adaptive, Multiple Dose Ranging Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Clinical Efficacy of Lonigutamab in Subjects with Thyroid Eye Disease (TED). Phase 1/2, multicenter, multiple dose clinical study designed to evaluate lonigutamab in subjects with TED.
• The leading Graves Ophthalmopathy Companies such as Immunovant Sciences GmbH, Horizon Pharma USA, Inc., Viridian Therapeutics, Inc., Tourmaline Bio, Inc., ACELYRIN Inc., Hoffmann-La Roche, Horizon Therapeutics USA, Inc., Lassen Therapeutics Inc., Novartis, Sling Therapeutics, Inc., Lassen Therapeutics, and others
• Promising Graves Ophthalmopathy therapies such as Batoclimab (IMVT 1401), RVT-1401, Teprotumumab, VRDN-001 10 mg/kg Drug, TOUR006 - 20 MG, IBI311, lonigutamab, Satralizumab, TEPEZZA, LASN01, CFZ533, linsitinib, LASN01, and others
Stay informed about the cutting-edge advancements in Graves Ophthalmopathy treatments. Download for updates and be a part of the revolution in care @ Graves Ophthalmopathy Clinical Trials Assessment- https://www.delveinsight.com/sample-request/graves-ophthalmopathy-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr
Graves Ophthalmopathy Emerging Drugs
• VRDN-001: Viridian
Viridian's lead product candidate, VRDN-001, is a potential best-in-class, IV monoclonal antibody targeting IGF-1R. VRDN-001 acts as a full antagonist of IGF-1R, and based on clinical data to date, has demonstrated robust clinical activity and was generally well-tolerated at Week 6 compared with the currently approved anti-IGF-1R antibody. Currently, the drug is in Phase III stage of its clinical trial for the treatment Graves' Ophthalmopathy.
• TOUR006: Tourmaline Bio
TOUR006 is a long-acting, fully human, anti-IL-6 monoclonal antibody with best-in-class potential and differentiated properties, including a naturally long half-life, low immunogenicity, and high binding affinity to IL-6. TOUR006 has been previously studied in 448 participants, including patients with autoimmune disorders, across six completed clinical trials. Tourmaline is developing TOUR006 in thyroid eye disease and atherosclerotic cardiovascular disease as its first two indications, with additional diseases under consideration. Currently, the drug is in Phase II Stage of its clinical trial for the treatment of Graves' Ophthalmopathy.
Learn more about Graves Ophthalmopathy Drugs opportunities in our groundbreaking Graves Ophthalmopathy Research and development projects @ Graves Ophthalmopathy Unmet Needs- https://www.delveinsight.com/sample-request/graves-ophthalmopathy-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr
Graves Ophthalmopathy Companies
Immunovant Sciences GmbH, Horizon Pharma USA, Inc., Viridian Therapeutics, Inc., Tourmaline Bio, Inc., ACELYRIN Inc., Hoffmann-La Roche, Horizon Therapeutics USA, Inc., Lassen Therapeutics Inc., Novartis, Sling Therapeutics, Inc., Lassen Therapeutics, and others.
Graves Ophthalmopathy pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Intravenous
• Subcutaneous
• Parenteral
• Topical
Graves Ophthalmopathy Products have been categorized under various Molecule types such as
• Recombinant fusion proteins
• Small molecule
• Monoclonal antibody
• Peptide
• Polymer
• Gene therapy
Discover the latest advancements in Graves Ophthalmopathy treatment by visiting our website. Stay informed about how we're transforming the future of disease @ MyeloGraves Ophthalmopathy fibrosis Market Drivers and Barriers, and Future Perspectives- https://www.delveinsight.com/sample-request/graves-ophthalmopathy-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr
Scope of the Graves Ophthalmopathy Pipeline Report
• Coverage- Global
• Graves Ophthalmopathy Companies- Immunovant Sciences GmbH, Horizon Pharma USA, Inc., Viridian Therapeutics, Inc., Tourmaline Bio, Inc., ACELYRIN Inc., Hoffmann-La Roche, Horizon Therapeutics USA, Inc., Lassen Therapeutics Inc., Novartis, Sling Therapeutics, Inc., Lassen Therapeutics, and others
• Graves Ophthalmopathy Therapies- Batoclimab (IMVT 1401), RVT-1401, Teprotumumab, VRDN-001 10 mg/kg Drug, TOUR006 - 20 MG, IBI311, lonigutamab, Satralizumab, TEPEZZA, LASN01, CFZ533, linsitinib, LASN01, and others
• Graves Ophthalmopathy Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Myelo Graves Ophthalmopathy fibrosis Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
For a detailed overview of our latest research findings and future plans, read the full details of Graves Ophthalmopathy Pipeline on our website @ Graves Ophthalmopathy Emerging Drugs and Companies- https://www.delveinsight.com/sample-request/graves-ophthalmopathy-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr
Table of Content
1. Introduction
2. Executive Summary
3. Graves Ophthalmopathy: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Graves Ophthalmopathy - DelveInsight's Analytical Perspective
7. Late Stage Products (Phase III)
8. VRDN-001: Viridian
9. Drug profiles in the detailed report…..
10. Mid Stage Products (Phase II)
11. TOUR006: Tourmaline Bio
12. Drug profiles in the detailed report…..
13. Early Stage Products (Phase I)
14. Drug name: Company name
15. Drug profiles in the detailed report…..
16. Preclinical and Discovery Stage Products
17. Drug name: Company name
18. Drug profiles in the detailed report…..
19. Inactive Products
20. Graves Ophthalmopathy Key Companies
21. Graves Ophthalmopathy Key Products
22. Graves Ophthalmopathy- Unmet Needs
23. Graves Ophthalmopathy- Market Drivers and Barriers
24. Graves Ophthalmopathy- Future Perspectives and Conclusion
25. Graves Ophthalmopathy Analyst Views
26. Graves Ophthalmopathy Key Companies
27. Appendix
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