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CINV Existing and Pipeline Drugs Market Outlook 2031: Expanding from US$ 1.9 Billion to US$ 3.2 Billion with an 5.8% CAGR

04-04-2025 11:26 AM CET | Health & Medicine

Press release from: Transparency Market Research

CINV Existing and Pipeline Drugs Market

CINV Existing and Pipeline Drugs Market

CINV Existing and Pipeline Drugs market has been experiencing significant growth, driven by increasing cancer prevalence, advancements in antiemetic therapies, and rising awareness regarding supportive cancer care. In 2021, the market was valued at US$ 1.9 billion, and it is projected to grow at a CAGR of 5.8% from 2022 to 2031. By the end of 2031, the market is expected to surpass US$ 3.2 billion. The increasing number of cancer patients undergoing chemotherapy and the demand for novel, more effective antiemetic drugs are key drivers for market expansion.

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Market Dynamics

1. Rising Cancer Prevalence and Chemotherapy Use
Cancer remains one of the leading causes of death worldwide, with millions of new cases diagnosed annually. A significant percentage of cancer patients undergo chemotherapy treatments, which frequently lead to nausea and vomiting, increasing the demand for effective antiemetic therapies.

2. Growing Adoption of Novel CINV Medications
The development of new-generation 5-HT3 receptor antagonists, NK1 receptor antagonists, and Hemp-based antiemetics is improving CINV management. These drugs provide better efficacy, prolonged relief, and fewer side effects, enhancing patient quality of life.

3. Increasing Awareness and Supportive Care Initiatives
Healthcare organizations and pharmaceutical companies are launching awareness campaigns to educate patients and caregivers about CINV prevention and management, leading to a higher adoption of antiemetic treatments.

4. Expansion of Drug Pipelines and Clinical Trials
Several pharmaceutical companies are actively investing in the development of novel antiemetic drugs, leading to a promising pipeline. Clinical trials for combination therapies and long-acting formulations are expected to enhance treatment efficacy in the coming years.

Key Challenges and Restraints

Despite the positive outlook, the market faces several challenges:

High Cost of Newer CINV Medications: Advanced antiemetics can be expensive, limiting access in certain regions.

Side Effects of Antiemetic Drugs: Some patients experience headaches, dizziness, or constipation as side effects.

Regulatory Hurdles: Strict approval processes for new drugs can delay market entry.

Competition from Generic Drugs: Increasing availability of generic antiemetics may impact revenue growth for branded drugs.

Top Manufacturers

GlaxoSmithKline plc
Helsinn Holding S.A.
Heron Therapeutics, Inc.
Merck & Co., Inc.
Tesaro, Inc.

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Future Trends and Opportunities

Several emerging trends are expected to shape the future of the CINV drugs market:

Development of Long-acting and Combination Therapies: Improving patient compliance and reducing dosing frequency.

Expansion of Hemp-based Treatments: Increasing adoption of medical Hemp for nausea relief.

Advancements in Personalized Medicine: Tailoring antiemetic treatments based on patient genetics and chemotherapy regimens.

Integration of Digital Health Solutions: AI-based platforms for CINV monitoring and management.

Market Segmentation

The CINV existing and pipeline drugs market is segmented based on drug class, distribution channel, and region.

1. By Drug Class

5-HT3 Receptor Antagonists: Ondansetron, Palonosetron, Granisetron.

NK1 Receptor Antagonists: Aprepitant, Fosaprepitant, Rolapitant.

Dopamine Receptor Antagonists: Metoclopramide, Domperidone.

Hemp-based Antiemetics: Dronabinol, Nabilone.

Corticosteroids: Dexamethasone.

2. By Distribution Channel

Hospital Pharmacies: Major distribution channel for prescription antiemetic drugs.

Retail Pharmacies: Increasing accessibility of over-the-counter and prescription CINV drugs.

Online Pharmacies: Rising popularity due to convenience and availability of specialized medications.

3. By Region

North America: Leading market share due to advanced healthcare infrastructure and high chemotherapy rates.

Europe: Growth driven by increasing cancer incidence and robust pharmaceutical R&D.

Asia-Pacific: Rapid expansion due to improving healthcare facilities and rising cancer awareness.

Latin America & Middle East/Africa: Emerging markets with growing demand for CINV treatments.

Conclusion

The global CINV existing and pipeline drugs market is set to grow significantly, driven by increasing cancer prevalence, innovations in antiemetic drug development, and rising awareness about supportive care. While challenges such as high drug costs and regulatory barriers exist, advancements in long-acting therapies, personalized medicine, and digital health integration will continue to drive the market forward. By 2031, improved access to effective CINV treatments will enhance the quality of life for cancer patients globally.

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About Transparency Market Research

Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyses information.

Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.

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