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Primary Ovarian Insufficiency Market Size Forecasted To Achieve 1.73 Billion By 2029 With Steady Growth
Primary Ovarian Insufficiency Market
What Is the Primary Ovarian Insufficiency Market Size and Projected Growth Rate?
The market size for primary ovarian insufficiency has seen a swift expansion in the past few years. The market size, which was $1.07 billion in 2024, is projected to reach $1.18 billion in 2025, at a compound annual growth rate (CAGR) of 10.1%. The growth recorded in the recent past can be linked to factors like the escalating incidences of autoimmune diseases, heightened stress levels, growing number of genetic mutations, an increase in women opting for delayed childbirth, and a rise in endocrine disorder occurrences.
Future years are projected to witness a swift expansion of the primary ovarian insufficiency market, with its predicted size reaching $1.73 billion in 2029 with a compound annual growth rate (CAGR) of 10.0%. This anticipated growth throughout the forecast period can be traced back to the rising adoption of assisted reproductive technologies, increased preference for fertility preservation alternatives, mounting emphasis on personalized medicine, and a growing attraction towards hormonal therapies as well as the escalating utilization of fertility preservation methods. The market forecast includes ongoing trends such as advancements in diagnostic technology, the incorporation of genetic testing, tech advancements in fertility preservation, breakthroughs in non-hormonal therapies, and the innovation of early detection biomarkers.
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What Are the Major Segments in the Primary Ovarian Insufficiency Market?
The primary ovarian insufficiency market covered in this report is segmented -
1) By Type: Hormone Replacement Therapy (HRT), Calcium and Vitamin D Supplements, In Vitro Fertilization (IVF), Stem Cell Therapy, Other Types
2) By Diagnosis Method: Blood Tests, Ultrasound Imaging, Genetic Testing
3) By Application: Less Than 20 Years Old, 20 To 30 Years Old, 30 To 45 Years Old, 45 Years Old And Older
4) By End-Users: Hospitals And Clinics, Specialty Fertility Centers
Subsegments:
1) By Hormone Replacement Therapy: Estrogen Therapy, Estrogen-Progestin Therapy, Transdermal Patches, Vaginal Estrogen Products, Oral Hormone Therapy
2) By Calcium And Vitamin D Supplements: Calcium Carbonate, Calcium Citrate, Vitamin D2 (Ergocalciferol), Vitamin D3 (Cholecalciferol), Combined Calcium + Vitamin D Formulations
3) By In Vitro Fertilization: Conventional In Vitro Fertilization, Intracytoplasmic Sperm Injection (ICSI), Egg Donation In Vitro Fertilization, Embryo Freezing And Transfer, Preimplantation Genetic Testing (PGT)
4) By Stem Cell Therapy: Autologous Stem Cell Therapy, Allogeneic Stem Cell Therapy, Mesenchymal Stem Cell (MSC) Therapy, Ovarian Stem Cell Transplantation
5) By Other Types: Psychological Counseling And Support Therapies, Assisted Reproductive Technologies (other than IVF), Immunomodulatory Therapies, Lifestyle And Dietary Interventions
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What Are The Driving Primary Ovarian Insufficiency Market Evolution?
The rise in autoimmune disorders is anticipated to fuel the expansion of the primary ovarian insufficiency market. Autoimmune disorders are diseases in which the body's immune system erroneously attacks and destroys its own healthy cells and tissues. This surge in autoimmune disorders is primarily attributed to genetic predisposition, where certain inherited genes increase vulnerability to immune system malfunctions. Primary ovarian insufficiency (POI) contributes to a deeper comprehension of autoimmune disorders by illustrating how hormonal imbalance and immune system dysregulation interplay, raising the chances of autoimmune diseases in the affected population. For example, Versorgungsatlas.de, a German organization, stated in November 2024, that in 2022, out of 73,241,305 insured individuals, 6,304,340 were diagnosed with at least one autoimmune disease. This accounted for a crude prevalence rate of 8.61%. Consequently, the escalating prevalence of autoimmune disorders is propelling the growth of the primary ovarian insufficiency market.
Which Firms Dominate The Primary Ovarian Insufficiency Market Segments?
Major companies operating in the primary ovarian insufficiency market are Mayo Clinic, Johns Hopkins Medicine, Baptist Health, Ferring Pharmaceuticals A/S, The Kingsley Natural Health Clinic, PreventionGenetics LLC, The Fertility Partnership (TFP) UK, Celmatix Inc., European Society of Human Reproduction and Embryology (ESHRE), Endocrine Society, IVIRMA Global, American Society for Reproductive Medicine (ASRM), TCM Healthcare (UK) Ltd., Bioscience Institute S.p.A., Sparsh Diagnostics Pvt. Ltd., Welling Homeopathy Clinics Pvt. Ltd., Bristol Menopause Clinic, Indira IVF Hospital Private Limited, Lawley Pharmaceuticals Pty. Ltd., OvaScience Inc.
What Are the Major Trends Shaping the Primary Ovarian Insufficiency Market?
The key players in the market for primary ovarian insufficiency are focusing on the development of innovative treatments like allogenic exosomal therapy to improve fertility and restore ovarian functionality. This therapy utilizes exosomes - extracellular vesicles which are derived from stem cells of a donor - to send signals for regeneration that promote tissue repair and reinstate ovarian functionality for patients afflicted with primary ovarian insufficiency. As an example, in October 2022, the FDA gave the green light to Vitti Labs LLC, a biotech company from the US, for the deployment of EV-Pure to treat primary ovarian insufficiency. This leverages the anti-inflammatory, regenerative, and immunomodulatory attributes of exosomes derived from mesenchymal stromal cells to reestablish fertility and ovarian functionality. This is a ready-to-use, cell-free therapy that negates the risks often associated with cell-based treatments, such as immune rejection or malignant transformation, and simultaneously delivers bioactive molecules geared towards promoting tissue repair and homeostasis.
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Which Is The Largest Region In The Primary Ovarian Insufficiency Market?
North America was the largest region in the primary ovarian insufficiency market in 2024. The regions covered in the primary ovarian insufficiency market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
Frequently Asked Questions:
1. What Is the Market Size and Growth Rate of the Primary Ovarian Insufficiency Market?
2. What is the CAGR expected in the Primary Ovarian Insufficiency Market?
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4. Which Region Is Leading the Primary Ovarian Insufficiency Market?
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