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Biocatalysis and Biocatalysts Market size to hit $1.24 Billion by 2037 | Top companies include DuPont de Nemours, Inc., BASF SE, Novozymes A/S, Lonza Group Ltd., Royal DSM Lockheed Martin

12-03-2025 01:27 PM CET | Chemicals & Materials

Press release from: Research Nester Pvt Ltd

Biocatalysis and Biocatalysts Market

Biocatalysis and Biocatalysts Market

Market Outlook and Forecast

The biocatalysis and biocatalysts market is gaining strong momentum as industries worldwide transition toward more sustainable, efficient, and cost-effective chemical processes. The global market is valued at USD 722.52 million in 2025 and is projected to reach USD 1.24 billion by 2037, progressing at a CAGR of 4.9% from 2025-2037. Growing preference for greener manufacturing routes, reduced dependency on hazardous chemicals, and the rising adoption of enzyme-based catalysis in pharmaceuticals, food processing, and industrial biotechnology are strengthening market expansion.

Biocatalysis - which utilizes natural catalysts such as enzymes and microorganisms - offers high selectivity, mild reaction conditions, and improved efficiency compared to conventional chemical catalysis. These attributes are fueling its application in drug synthesis, specialty chemicals, biofuels, detergent formulations, and flavor development. As regulatory bodies tighten sustainability norms, the industry is accelerating its shift toward bio-based catalytic systems that minimize waste and enhance reaction productivity.

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Regional Performance Highlights

North America remains a key contributor to global demand, supported by strong investments in pharmaceutical R&D, rapid adoption of enzyme technology, and an ecosystem of biotechnology innovators. The region is expected to hold 34% market share by 2037, driven by advancements in precision biomanufacturing, biologics production, and enzyme-engineered synthesis pathways. The United States leads with substantial research funding, strong presence of contract manufacturing organizations (CMOs), and expansion of industrial biotechnology clusters.

Europe continues to advance sustainable chemical production under its Green Deal and circular economy goals. The region's strict regulatory frameworks are pushing companies toward bio-based alternatives and eco-efficient catalytic systems. Germany, the Netherlands, Denmark, and Switzerland are at the forefront of enzyme engineering, specialty chemical manufacturing, and fermentation-based production. European firms are adopting biocatalysts to improve process yields, reduce carbon footprints, and comply with REACH and ESG-driven operational benchmarks.

Asia Pacific is emerging as the fastest-growing regional market due to extensive investments in industrial enzymes, biotechnology infrastructure, and fermentation technologies. China, India, Japan, and South Korea are integrating biocatalysis into pharmaceuticals, food processing, textile finishing, and biofuel refining. Rising focus on sustainable industrial production, competitive manufacturing costs, and government-backed biotech innovation programs are elevating the region's long-term market potential.

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Market Segmentation

The hydrolases segment continues to dominate the market and is expected to account for 41% share during the forecast period. Hydrolases - including proteases, lipases, and amylases - enable efficient biomass breakdown, food processing, detergent performance enhancement, ingredient modification, and pharmaceutical intermediate production. Their broad substrate compatibility and stable operational profile make them indispensable across both industrial and laboratory-scale applications.

The food & beverages segment is another major revenue generator, projected to hold 33% market share. Biocatalysts are widely used to enhance flavor development, sugar modification, fermentation efficiency, and nutritional improvements in processed foods. The growing demand for clean-label, minimally processed, and health-oriented food products is encouraging food manufacturers to adopt enzymatic solutions that ensure high-quality, consistent, and sustainable production.

Across industries, the shift toward enzyme-mediated catalysis is enabling faster reaction times, lower energy requirements, reduced solvent usage, and improved environmental performance - supporting global sustainability goals and broader industrial decarbonization strategies.

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Top Market Trends

1. Surge in Sustainable Biomanufacturing and Green Chemistry Adoption

Sustainability is reshaping the Biocatalysis and Biocatalysts Market as companies prioritize low-emission, biodegradable, and energy-efficient manufacturing processes. Biocatalysts are becoming a preferred alternative to metal-based catalysts and harsh chemical reagents, helping industries reduce waste generation and improve reaction specificity. Recent initiatives in the EU and North America highlight the shift toward renewable feedstocks, green solvents, and enzyme-enabled production lines for pharmaceuticals, agrochemicals, and industrial chemicals.

For example, several multinational chemical producers have recently integrated enzymatic catalysis into synthetic pathways to reduce process steps and comply with ESG performance metrics. This shift is expected to accelerate as global organizations commit to carbon neutrality, circular production, and environmentally responsible manufacturing.

2. Breakthroughs in Enzyme Engineering and Computational Protein Design

Technological innovation is transforming how biocatalysts are developed and optimized. AI-driven protein modeling, directed evolution, CRISPR-based pathway engineering, and high-throughput screening are enabling the creation of custom-designed enzymes with superior stability, specificity, and reaction efficiency. These advancements are opening doors to new applications in chiral synthesis, specialty polymers, and recombinant enzyme production.

Recent examples include the introduction of engineered transaminases and dehydrogenases optimized for pharmaceutical active ingredient (API) synthesis. Companies are increasingly adopting digital enzyme design platforms to accelerate R&D timelines and enhance commercial scalability.

3. Rapid Expansion of Biocatalysis in Pharmaceuticals and Life Sciences

Biocatalysis is witnessing expanding adoption in drug manufacturing, particularly for producing complex molecules, chiral compounds, and biologics. The push for cost-efficient, high-yield, and environmentally compliant processes is driving pharmaceutical companies to integrate enzyme-based synthesis throughout the value chain.

Within the last year, several leading pharmaceutical manufacturers have announced collaborations with biotechnology firms to develop enzyme libraries enabling streamlined synthesis pathways for APIs and intermediates. The rise of personalized medicine, biologics, and biosimilars further elevates demand for advanced enzyme technology.

4. Growing Penetration in Food, Beverages, and Specialty Consumer Products

Consumer demand for natural, additive-free, and label-friendly food ingredients is creating new opportunities for enzymatic processing. Enzymes are widely used for sugar conversion, flavor enhancement, texture improvement, and allergen reduction. The clean-label movement is prompting food companies to replace synthetic chemicals with biological catalysts that offer safer, more sustainable, and more cost-effective production processes.

Asia Pacific and Europe are currently seeing rapid integration of biocatalysis into dairy processing, beverage clarification, bakery ingredients, and plant-based protein formulation.

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Recent Company Developments

The Biocatalysis and Biocatalysts Market has experienced notable advancements, strategic investments, and cross-industry collaborations over the past 12 months. Key developments include:

1. Novozymes A/S - Introduced new enzyme solutions for sustainable chemical production and expanded its bioinnovation portfolio following its merger with Chr. Hansen.

2. DSM-Firmenich - Strengthened its biocatalysis platform through investments in fermentation capacity and launched new specialty enzymes for food and nutritional applications.

3. Codexis, Inc. - Announced a series of engineered enzyme launches tailored for pharmaceutical synthesis, along with multiple new biopharma partnerships.

4. BASF SE - Expanded its biocatalyst product line and invested in R&D projects aimed at developing enzyme-based alternatives for specialty chemical synthesis.

5. DuPont Industrial Biosciences - Advanced its enzyme offerings for textile finishing and bio-based material production, focusing on performance enhancement and sustainability.

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Related News -
https://www.linkedin.com/pulse/why-ph-adjusters-essential-across-modern-manufacturing-e6nbf
https://www.linkedin.com/pulse/why-does-polyethylene-play-critical-role-modern-industries-qvmwf

Contact Data

AJ Daniel
Corporate Sales, USA
Research Nester
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About Research Nester

Research Nester is a one-stop service provider with a client base in more than 50 countries, leading in strategic market research and consulting with an unbiased and unparalleled approach towards helping global industrial players, conglomerates and executives for their future investment while avoiding forthcoming uncertainties. With an out-of-the-box mindset to produce statistical and analytical market research reports, we provide strategic consulting so that our clients can make wise business decisions with clarity while strategizing and planning for their forthcoming needs and succeed in achieving their future endeavors. We believe every business can expand to its new horizon, provided a right guidance at a right time is available through strategic minds.

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